Zinc + Quercetin Halts Viral Replication


Finding treatment for the COVID-19 is essential in minimizing the number of deaths from the virus. Two drugs that were previously under investigation for this are hydroxychloroquine and chloroquine. Both hydroxychloroquine and chloroquine are quinoline medications used to treat or prevent malaria. They are also used to treat symptoms of rheumatoid arthritis and systemic lupus erythematosus.

I have researched the effects of zinc/zinc ionophore supplementation on viral replication. According to  one published study, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182877, chloroquine acts as a zinc ionophore. Simply put, this means is it able to transport zinc ions across the lipid membrane into cells, where it (the zinc) can stop viral replication. This is likely why  hydroxychloroquine can be effective in treating COVID-19.

I was encouraged when President Trump mentioned doctors were prescribing hydroxychloroquine with zinc at one of his briefings early on. Later on, he told us he was taking it prophylactically. This supports the theory that hydroxychloroquine acts as a zinc ionophore and implies that an adequate supply of zinc is an essential part of a treatment protocol. 
It is common knowledge among holistic health practitioners that zinc inhibits viral replication. Zinc is an essential mineral for multiple aspects of the immune system, including the normal development, differentiation, and function of cells belonging to both innate and acquired immunity. Increased intracellular zinc concentrations inhibit RNA-dependent RNA polymerases and other proteins essential for the completion of different phases of virus life cycle.

Many people are deficient in zinc.  This can be caused by inadequate dietary intake or poor gastrointestinal absorption.  Another cause may be the lack of zinc in soil due to the modern farming practices of utilizing herbicides, fungicides and pesticides. Therefore, I was not surprised when I initially heard several news reports stating one of the symptoms of Covid-19 is decreased sense of smell and taste. My nutritional studies have taught me a decrease in both senses is often a sign of zinc deficiency.

Zinc, along with hydroxychloroquine or chloroquine, will likely halt COVID-19.  However,  both drugs are not without side effects and contraindications.

There is a safer alternative to hydroxychloroquine and chloroquine.  It is called quercetin, a plant flavonoid found in fruits and vegetables.  Like hydroxychloroquine and chloroquine, it also acts as a zinc ionophore.  It has the same mechanism of action, allowing zinc pass through the cell wall and into the cell, where it can halt viral replication. Since hydroxychloroquine and chloroquine have side effects and also seem to be in short supply, it certainly makes sense to consider Quercetin as a viable alternative.

Regarding the best form of supplemental quercetin to take, according to one published nutritional study I found, Quercetin, Inflammation and Immunity, quercetin glycoside is the most bioavailable form. 
Always with your healthcare practitioner before taking any herbal supplement or natural product.